| Pick | Team | Image | Player | Position | School | Height | Weight | 40 Time |
| 1 | Kansas City Chiefs |  | Luke Joeckel | OT | Texas AM | 6/6 | 306 | 5.30 |
| 2 | Jacksonville Jaguars |  | Eric Fisher | OT | Central Michigan | 6/7 | 306 | 5.05 |
| 3 | Oakland Raiders |  | Sharrif Floyd | DT | Florida | 6/3 | 297 | 4.92 |
| 4 | Philadelphia Eagles |  | Dion Jordan | OLB/DE | Oregon | 6/6 | 248 | 4.60 |
| 5 | Detroit Lions |  | Lane Johnson | OT | Oklahoma | 6/6 | 305 | 4.72 |
| 6 | Cleveland Browns |  | Barkevious Mingo | OLB/DE | LSU | 6/4 | 241 | 4.58 |
| 7 | Arizona Cardinals |  | Geno Smith | QB | West Virginia | 6/2 | 215 | 4.59 |
| 8 | Buffalo Bills |  | Ryan Nassib | QB | Syracuse | 6/3 | 227 | 5.06 |
| 9 | New York Jets |  | Ezekiel Ansah | DE | BYU | 6/3 | 270 | 4.63 |
| 10 | Tennessee Titans |  | Star Lotulelei | DT | Utah | 6/2 | 311 | 5.25 |
| 11 | San Diego Chargers |  | Tavon Austin | WR | West Virginia | 5/11 | 185 | 4.35 |
| 12 | Miami Dolphins |  | Sheldon Richardson | DT | Missouri | 6/2 | 295 | 5.02 |
| 13 | New York Jets (via Tampa Bay) | | Dee Milliner | CB | Alabama | 6/0 | 201 | 4.37 |
| 14 | Carolina Panthers |  | Chance Warmack | OG | Alabama | 6/2 | 317 | 5.49 |
| 15 | New Orleans Saints |  | Johnathan Cooper | OG | North Carolina | 6/2 | 311 | 5.07 |
| 16 | St. Louis Rams |  | Kenny Vaccaro | S | Texas | 6/0 | 214 | 4.64 |
| 17 | Pittsburgh Steelers |  | Jarvis Jones | OLB | Georgia | 6/2 | 242 | 4.85 |
| 18 | Dallas Cowboys |  | D.J. Hayden | CB | Houston | 5/11 | 191 | 4.38 |
| 19 | New York Giants |  | Desmond Trufant | CB | Washington | 6/0 | 184 | 4.40 |
| 20 | Chicago Bears |  | D.J. Fluker | OT | Alabama | 6/5 | 335 | 5.31 |
| 21 | Cincinnati Bengals |  | Sylvester Williams | DT | North Carolina | 6/3 | 320 | 5.24 |
| 22 | St. Louis Rams (via Washington) | | Cordarrelle Patterson | WR | Tennessee | 6/2 | 220 | 4.42 |
| 23 | Minnesota Vikings |  | Xavier Rhodes | CB | Florida State | 6/1 | 212 | 4.43 |
| 24 | Indianapolis Colts |  | Bjoern Werner | DE | Florida State | 6/3 | 266 | 4.83 |
| 25 | Minnesota Vikings (via Seattle) | | Manti Te'o | MLB | Notre Dame | 6/2 | 255 | 4.71 |
| 26 | Green Bay Packers |  | Eddie Lacy | RB | Alabama | 5/11 | 221 | 4.55 |
| 27 | Houston Texans |  | Justin Hunter | WR | Tennessee | 6/4 | 196 | 4.44 |
| 28 | Denver Broncos |  | Cornellius Carradine | DE | Florida State | 6/4 | 276 | 4.87 |
| 29 | New England Patriots |  | Alec Ogletree | OLB | Georgia | 6/3 | 232 | 4.62 |
| 30 | Atlanta Falcons |  | Kevin Minter | MLB | LSU | 6/0 | 242 | 4.84 |
| 31 | San Francisco 49ers |  | Jonathan Cyprien | S | Florida International | 6/0 | 209 | 4.45 |
| 32 | Baltimore Ravens |  | Damontre Moore | DE | Texas AM | 6/4 | 250 | 4.95 |
